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Narcolepsy

Narcolepsy is a chronic neurological disorder that affects the brain’s ability to regulate sleep-wake cycles. People with narcolepsy experience excessive daytime sleepiness and sudden, uncontrollable episodes of falling asleep during the day. These episodes can occur at any time, such as during work, conversations, or other activities, and can significantly impact daily life and functioning.

Key Features of Narcolepsy

  1. Excessive Daytime Sleepiness (EDS)
    • People with narcolepsy experience overwhelming drowsiness and fatigue during the day, regardless of how much sleep they get at night.
    • Individuals may fall asleep suddenly and without warning, leading to potential safety issues and difficulties at work or school.
  2. Cataplexy
    • Cataplexy is a sudden loss of muscle tone, often triggered by strong emotions such as laughter, excitement, or anger.
    • It can range from mild weakness (such as drooping eyelids or knees buckling) to complete physical collapse while remaining conscious.
  3. Sleep Paralysis
    • People with narcolepsy may experience temporary inability to move or speak while falling asleep or waking up.
    • These episodes typically last a few seconds to a couple of minutes and can be frightening.
  4. Hypnagogic or Hypnopompic Hallucinations
    • These are vivid and often frightening dream-like experiences that occur while falling asleep (hypnagogic) or waking up (hypnopompic).
    • They can involve visual, auditory, or tactile sensations.
  5. Disrupted Nighttime Sleep
    • People with narcolepsy often have fragmented sleep with frequent awakenings, despite the excessive sleepiness they experience during the day.

Types of Narcolepsy

  1. Type 1 Narcolepsy (Narcolepsy with Cataplexy)
    • Characterized by excessive daytime sleepiness and cataplexy.
    • Often associated with low levels of hypocretin, a neurotransmitter that helps regulate wakefulness.
  2. Type 2 Narcolepsy (Narcolepsy without Cataplexy)
    • Characterized by excessive daytime sleepiness but without cataplexy.
    • Hypocretin levels are typically normal in individuals with Type 2 narcolepsy.

Causes and Risk Factors of Narcolepsy

  • Genetics: A family history of narcolepsy can increase the risk of developing the disorder.
  • Autoimmune Response: Narcolepsy is believed to involve an autoimmune response that leads to the loss of hypocretin-producing neurons in the brain.
  • Environmental Triggers: Infections, stress, or hormonal changes may trigger the onset of narcolepsy in susceptible individuals.

Diagnosis and Treatment of Narcolepsy

  • Diagnosis: Narcolepsy is diagnosed through clinical evaluation, including a detailed medical history and sleep studies such as polysomnography and the Multiple Sleep Latency Test (MSLT).
  • Treatment: While there is no cure for narcolepsy, symptoms can be managed with a combination of medication, lifestyle changes, and behavioral strategies. Treatments may include:
    • Stimulants or wake-promoting medications to reduce daytime sleepiness.
    • Antidepressants or sodium oxybate to manage cataplexy and other symptoms.
    • Scheduled naps and good sleep hygiene to improve alertness.

Impact on Daily Life

Narcolepsy can significantly affect daily life, work, and social interactions. Individuals with narcolepsy may need to take extra precautions to ensure safety, such as avoiding activities that could be dangerous if a sleep episode occurs (e.g., driving) and making adjustments in their work or school environment.

It is essential for individuals with narcolepsy to work closely with healthcare providers to develop a personalized treatment plan and manage their symptoms effectively.

Schedule A Consultation

Narcolepsy and other sleep disorders can be highly disruptive. Sleep deprivation can increase the risk of depression and heart disease, leaving you feeling constantly tired and less alert. Both your physical and mental health may be compromised.

That’s why Norelle Health is dedicated to helping patients treat their sleep disorders. Through lifestyle changes and the latest treatments, Dr. Chernobilsky assists his patients in getting the restful sleep they deserve. If you are experiencing sleep-related symptoms, schedule a consultation today. We look forward to providing the help you need for a full night’s rest.

Talk To An Expert

Meet Norelle Health

Boris Chernobilsky, MD is double board-certified in Otolaryngology-Head and Neck Surgery and Sleep Medicine. He is a member of the American Academy of Otolaryngology-Head and Neck Surgery and the International Sleep Surgical Society. He specializes in all manner of sleep and airway surgery with particular... Learn More »