Overview
Restless legs syndrome, also called Willis-Ekbom disease, is a neurologic condition that produces an uncomfortable, hard-to-describe urge to move the legs. The sensations typically appear or worsen in the evening and during periods of rest, and they ease with movement.
Because the symptoms peak at bedtime, restless legs syndrome commonly disrupts the ability to fall asleep and can lead to chronic sleep loss and daytime fatigue. Many people also have periodic limb movements during sleep that further fragment rest.
Restless legs syndrome is diagnosed mainly from the history and is often managed with sleep medicine or neurology. Norelle Health can help recognize the pattern, check for contributing factors, and coordinate care, including evaluation of any coexisting sleep-breathing problem.
Symptoms and key features
People describe creeping, crawling, aching, or tingling sensations deep in the legs, along with a strong need to move them for relief. Walking, stretching, or rubbing the legs typically helps temporarily.
The timing is a key feature: symptoms are worse in the evening and at night and tend to be most disruptive when a person is trying to relax or fall asleep.

Living with restless leg syndrome? The next step is a quiet, unhurried conversation.
Causes and risk factors
Restless legs syndrome is linked to how the brain uses dopamine and to the body's iron stores. Low iron is an important and treatable contributor.
It can run in families and becomes more common with age. Pregnancy, kidney disease, and certain medications, including some antihistamines and antidepressants, can trigger or worsen symptoms.

How it is diagnosed
Diagnosis is based on the history, focusing on the urge to move, the relief with movement, and the evening or nighttime pattern. Blood tests are often done to check iron stores and screen for related conditions.
A sleep study is not usually needed to diagnose restless legs syndrome, but it may be used when periodic limb movements or another sleep disorder such as sleep apnea is suspected.

Treatment options
Treatment depends on severity:
- Checking iron stores and treating low iron when present
- Reviewing and adjusting medications that can worsen symptoms
- Limiting caffeine, alcohol, and nicotine, especially in the evening
- Regular activity, stretching, and consistent sleep habits
- Prescription medications for moderate to severe symptoms, managed by a specialist
Many people improve once iron status and contributing factors are addressed.

When to seek care
Consider an evaluation when leg discomfort regularly interferes with falling asleep or with daytime functioning, or when self-care measures have not helped. Let your clinician know about any medications, since some can trigger symptoms.
Clinical references
- American Academy of Sleep Medicine: https://sleepeducation.org
Medical review
This page is a patient-education resource reviewed by the responsible Norelle Health clinician before publication. It does not replace an in-person evaluation. If symptoms are severe or rapidly worsening, seek immediate medical care.
Specialists who treat restless leg syndrome

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(212) 444-8006Frequently Asked Questions
Most people describe an uncomfortable urge to move the legs, with sensations such as crawling, aching, or tingling. The feeling eases with movement and is usually worst in the evening or at night.
Restless legs syndrome follows a daily pattern, with symptoms peaking in the evening and at night. This timing is one of the features used to make the diagnosis and is also why it commonly disrupts sleep.
Yes. Low iron stores are an important and treatable contributor. Checking and correcting iron levels is often one of the first steps in management.
No. Leg cramps are painful muscle contractions, while restless legs syndrome is an urge to move the legs with uncomfortable sensations that ease with movement. The two are managed differently.
A sleep study is not usually required to diagnose restless legs syndrome. It may be recommended if periodic limb movements or another sleep disorder such as sleep apnea is suspected.
Some medications, including certain antihistamines and antidepressants, can trigger or worsen symptoms. Reviewing your medication list is part of the evaluation.
Limiting caffeine, alcohol, and nicotine, staying active, stretching, and keeping a regular sleep schedule can help. If symptoms persist, a clinician can check iron levels and discuss further treatment.
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